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Four Texans Invent Way To Use Gene As Cancer Detector-Predictor
Four Texans Invent Way To Use Gene As Cancer Detector-Predictor | hou_txbz, ovarian cancer, cancer, diagnostic tool, Xiadong Cheng, Fang Mel, League City, Travis Young, Galveston, Jinsong Liu, 7897340, gene 101, TSG 101, prognostic, marker, University of Texas, Ras, oncogenic, therapeutic target,

U.S. Patent 7,897,340: Use of tumor susceptibility gene 101 (TSG 101) as a prognostic and diagnostic marker

Texas Business reports:  Four Texans invented a way using of gene as a diagnostic tool for ovarian cancer, as well as determining the likely outcome if cancer is detected.

Xiaodong Cheng and Fang Mel, both of League City, Travis Young of Galveston and Jinsong Liu of Houston received U.S. Patent 7,897,340 for “Use of tumor susceptibility gene 101 (TSG 101) as a prognostic and diagnostic marker.”  

The four filed for the patent on February 13, 2007.

The patent assignee is the Board of Regents of the University of Texas System.

The four’s inventions discloses the link between oncogenic Ras and TSG101 and the negative effect of TSG101 on the expression of p21 in ovarian cancer.

The present also discloses the use of TSG101 as a prognostic, diagnostic marker and a potential therapeutic target in cancer, especially ovarian cancer.